ARHG6 Polyclonal Antibody - BT-AP14310

ARHG6 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14310-20, BT-AP14310-50, BT-AP14310-100

Citations, Manuals and MSDS Available upon request.

Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation.

Research Areas: Signal transduction

Target Protein: ARHGEF6

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Rho guanine nucleotide exchange factor 6

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q15052; Mouse: Q8K4I3; Rat: Q5XXR3

Synonyms: Rho guanine nucleotide exchange factor 6;Alpha-Pix;COOL-2;PAK-interacting exchange factor alpha;Rac/Cdc42 guanine nucleotide exchange factor 6

GeneID: Human: 9459

Research Use Only