ARHGEF10 Polyclonal Antibody - E-AB-10831

ARHGEF10 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-10831-60, E-AB-10831-120, E-AB-10831-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ARHGEF10

Target Synonym: ARHGA; ARHGEF10; DKFZp686H0726; GEF10; KIAA0294; MGC131664; Rho guanine nucleotide exchange factor (GEF) 10; Rho guanine nucleotide exchange factor 10

Research Areas: Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O15013

Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. ARHGEF10 (rho guanine nucleotide exchange factor 10), also known as GEF10 or KIAA0294, is a 1, 369 amino acid protein that contains one DBL-homology domain and is thought to play a role in myelination of peripheral nerves, specifically during development. ARHGEF10 is expressed as four alternatively spliced isoforms that are present at low levels in ovary, lung, testis and kidney, with considerably higher expression in the central and peripheral nervous systems.

Concentration: 0.3 mg/mL

Immunogen: Recombinant protein of human ARHGEF10

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only