Product Description

ARHGEF6 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16170-60, E-AB-16170-120, E-AB-16170-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ARHGEF6

Target Synonym: Alpha Pix; Alpha-Pix; ARHG6; ARHGEF6; COOL 2; COOL-2; COOL2; Mental retardation; X linked 46; MRX46; PAK interacting exchange factor alpha; PAK-interacting exchange factor alpha; PIXA; Rac/Cdc42 guanine exchange factor (GEF) 6; Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6; Rac/Cdc42 guanine nucleotide exchange factor 6; Rho guanine nucleotide exchange factor 6

Research Areas: Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q15052

Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation.

Concentration: 0.7 mg/mL

Immunogen: Synthetic peptide of human ARHGEF6

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only