Product Description

ARL2BP Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61595-50, BS61595-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: ADP-ribosylation factors (ARFs) are important in eukaryotic vesicμlar trafficking pathways and they play an essential role in the activation of phospholipase D (PC-PLD). ARL2 (ADP-ribosylation factor-like protein 2) functions as a component of a secretory pathway that is involved in the calcium-dependent release of acetylcholine. Additionally, ARL2 plays a role in the folding of tubμle proteins, thereby playing an important role in microtubμle dynamics and cell cycle progression. BART1 (Binder of ARL2 protein 1), also known as ARL2BP (ADP-ribosylation factor-like protein 2-binding protein), is a 163 amino acid protein that interacts with GTP-bound ARL2 complexes and therefore may play a role in modμlating ARL2 activity. Though predominantly cytosolic, BART1 can enter the mitochondria and bind the adenine nucleotide transporter when bound to ARL2. There are two isoforms of BART1 that are produced as a resμlt of alternative splicing events.

Category: Primary Antibody

Reactivity: Human, Rat

Host: Rabbit

Applications: WB

Alternate Names: ADP-ribosylation factor-like protein 2-binding protein, ARF-like 2-binding protein, ARL2-binding protein, Binder of ARF2 protein 1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 104-148 of Human ARL2BP.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 100% (by SDS-PAGE).

Specificity: ARL2BP polyclonal antibody detects endogenous levels of ARL2BP protein.

Molecular Weight: ~ 18 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9Y2Y0

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only