Arrestin-β-2 Monoclonal Antibody - RA10806

Arrestin-β-2 Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA10806-50, RA10806-100

Citations, Manuals and MSDS Available upon request.

Background: arrestin beta 2 (ARRB2) Homo sapiens Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012],

Condition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IF/ICC

Species Cross-Reactivity: Human; Mouse; Rat; Pig

GeneID (Human): 409

SWISS: P32121

Source: Mouse

Research Use Only