Arrestin-C rabbit pAb - ES6145

Arrestin-C rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6145-50, ES6145-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016],

Alternate Name: ARR3; ARRX; CAR; Arrestin-C; Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human ARRC. AA range:339-388

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 40kD

Human Gene ID: 407

Human SWISS Prot NO: P36575

Subcellular Location: Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment.

Research Use Only