ARSE Polyclonal Antibody-BS5621

ARSE Polyclonal Antibody

Catalogue Numbers: BS5621-50, BS5621-100

Sizes: 50µl, 100µl

Alternative Name: Arylsulfatase E; ASE; ARSE

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P51690

Host: Rabbit

Reactivity: Human

Applications: WB ICC

All Applications: WB: 1:500~1:1000
ICC: 1:50~1:200

Background: Arylsulfatase E, also known as CDPX, CDPX1 or CDPXR, is a 589 amino acid Golgi apparatus protein expressed in the pancreas, liver and kidney. Belonging to the sulfatase family, Arylsulfatase E may be essential for the correct composition of cartilage and bone matrix during development. Inhibited by warfarin, Arylsulfatase E activity occurs under optimal pH and temperature. Defects in the gene encoding Arylsulfatase E are the cause of chondrodysplasia punctata X-linked recessive type 1 (CDPX1), which is characterized by aberrant bone mineralization, severe underdevelopment of nasal cartilage and distal phalangeal hypoplasia. Arylsulfatase E has no activity toward steroid sulfates.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ARSE polyclonal antibody detects endogenous levels of ARSE protein.

Bioworld Molecular Weight: ~ 66 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of ARSE polyclonal antibody at 1:500 dilution
Lane 1: Hela cell lysate
Lane 2: HEK293T cell lysate

Immunogen: Synthetic peptide, corresponding to amino acids 208-253 of Human ARSE.

Conjugate: Unconjugated

Modification: Unmodified