Artemis (phospho Ser516) Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA22096-50, RA22096-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: DNA cross-link repair 1C (DCLRE1C) Homo sapiens This gene encodes a nuclear protein that is involved in V (D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014], Reactivity: Human, Mouse Host: Rabbit Applications: WB, IHC-p, IF (paraffin section), ELISA Alternate Names: DCLRE1C, ARTEMIS, ASCID, SCIDA, SNM1C, Protein artemis, DNA cross-link repair 1C protein, Protein A-SCID, SNM1 homolog C, hSNM1C, SNM1-like protein Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. Molecular Weight: 78 Protein Molecular Weight (kDa): 78 Storage: -20°C/1 year Human Gene ID: 64421 Human SwissProt Number: Q96SD1 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only