Product Description

Artn Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA22098-50, RA22098-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: artemin (ARTN) Homo sapiens This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma. [provided by RefSeq, Aug 2016],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: IHC-p, IF (paraffin section), ELISA

Alternate Names: Artemin (Enovin;Neublastin)

Clonality: Polyclonal

Dilution: IHC-p 1:50-200, ELISA 1:10000-20000

Storage: -20°C/1 year

Human Gene ID: 9048

Human SwissProt Number: Q5T4W7

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only