ARVC Rabbit Polyclonal Antibody - RA31172

ARVC Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31172-50, RA31172-100

Citations, Manuals and MSDS Available upon request.

Background: Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein. [provided by RefSeq, Jun 2010],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.257% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000

Alternative Names: Armadillo repeat protein deleted in velo-cardio-facial syndrome

Applications: WB

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 421

Protein MW (KDa): 105

SWISS: O00192

Source: Rabbit

Research Use Only