Product Description

ARVC Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31172-50, RA31172-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein. [provided by RefSeq, Jun 2010],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Alternate Names: Armadillo repeat protein deleted in velo-cardio-facial syndrome

Clonality: Polyclonal

Dilution: WB 1:500-2000

Molecular Weight: 105

Protein Molecular Weight (kDa): 105

Storage: -20°C/1 year

Human Gene ID: 421

Human SwissProt Number: O00192

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.257% sodium azide.

Research Use Only