Product Description

ARVCF Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65730-50, BS65730-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit

Host: Rabbit

Applications: WB

Alternate Names: Armadillo repeat gene deletes in velocardiofacial syndrome, Armadillo repeat protein, Armadillo repeat protein deleted in velo cardio facial syndrome, Armadillo repeat protein deleted in velo-cardio-facial syndrome, ARVC_HUMAN, Arvcf, FLJ35345, OTTHUMP00000028704, OTTHUMP00000198346, OTTHUMP00000198347, OTTHUMP00000198348.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human ARVCF:501-600/962

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: ARVCF Polyclonal Antibody detects endogenous levels of ARVCF protein.

Molecular Weight: 105 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O00192

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only