Product Description

ASAH2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-62491-60, E-AB-62491-120, E-AB-62491-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ASAH2

Target Synonym: ASAH2; BCDase; HNAC1; LCDase; N-CDase; NCDase

Research Areas: Cancer,Metabolism,Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9NR71

Background: Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).[supplied by OMIM, Mar 2008]

Concentration: 1 mg/mL

Immunogen: Recombinant protein of human ASAH2

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:1000-1:2000

Calculated MW: 81kDa/85kDa

Observed MW: 100kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only