Product Description

ASB8 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-10961-60, E-AB-10961-120, E-AB-10961-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ASB8

Target Synonym: Ankyrin repeat and SOCS box containing 8; Ankyrin repeat and SOCS box protein 8; ASB 8; ASB-8; ASB8; ASB8; FLJ21255; MGC5540; OTTHUMP00000237000; OTTHUMP00000237001; OTTHUMP00000237007; OTTHUMP00000237009; OTTHUMP00000237010; PP14212

Research Areas: Cancer, Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9H765

Background: ASB-8 (ankyrin repeat and SOCS box-containing 8) is a 288 amino acid member of the ASB family that contains one SOCS box domain and four ANK repeats. Localized to the cytoplasm, ASB-8 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. The highest level of ASB-8 expression has been detected in skeletal muscle. ASB-8 is also expressed in heart, brain, placenta, liver, kidney and pancreas.

Concentration: 0.7 mg/mL

Immunogen: Recombinant protein of human ASB8

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:25-1:100

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only