Product Description

ASCC2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16227-60, E-AB-16227-120, E-AB-16227-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ASCC2

Target Synonym: 1700011I11Rik; 2610034L15Rik; Activating signal cointegrator 1 complex subunit 2; AI482016; ASC 1 complex subunit p100; ASC-1 complex subunit p100; ASC1P100; ASCC 2; Ascc2; ASCC2; AW046480; FLJ21588; OTTMUSP00000005258; p100; RGD1561422; RP23-280J3.3; Trip4 complex subunit p100

Research Areas: Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9H1I8

Background: ASCC2 (activating signal cointegrator 1 complex subunit 2), also known as ASC1P100, is a 757 amino acid protein that is ubiquitously expressed and contains one CUE domain.The gene encoding ASCC2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

Concentration: 0.7 mg/mL

Immunogen: Synthetic peptide of human ASCC2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 86kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only