ASCL1 rabbit pAb - ES8645

ASCL1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8645-50, ES8645-100

Citations, Manuals and MSDS Available upon request.

Background: achaete-scute family bHLH transcription factor 1 (ASCL1) Homo sapiens This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008],

Alternate Name: Achaete-scute homolog 1 (ASH-1; hASH1; Class A basic helix-loop-helix protein 46; bHLHa46)

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: IHC-p 1:50-200, ELISA 1:10000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthetic peptide from human protein at AA range: 190-236

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 429

Human SWISS Prot NO: P50553

Subcellular Location: Nucleus

Research Use Only