ASIC1 rabbit pAb - ES8643

ASIC1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8643-50, ES8643-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012],

Alternate Name: Acid-sensing ion channel 1 (ASIC1; Amiloride-sensitive cation channel 2, neuronal; Brain sodium channel 2; BNaC2)

Source: Rabbit

Applications: WB; IHC; IF; IHC-f; ELISA

Dilution: WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthetic peptide from human protein at AA range: 220-280

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 55kD

Human Gene ID: 41

Human SWISS Prot NO: P78348

Subcellular Location: Cell membrane; Multi-pass membrane protein. Localizes in synaptosomes at dendritic synapses of neurons. Colocalizes with DLG4 (By similarity).

Research Use Only