Product Description

ASIP Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8554-50, BS8554-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: In mice, the agouti gene encodes a paracrine signaling molecμle that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adμlt-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimμlating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regμlating lipid metabolism in adipocytes.

Category: Primary Antibody

Reactivity: Mouse, Rat

Host: Rabbit

Applications: IHC-P

Alternate Names: ASP, AGSW, AGTI, AGTIL, SHEP9, ASIP

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-132 of human ASIP (NP_001663.2).

Dilution: IHC-P, 1:50 - 1:100

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: ASIP polyclonal antibody detects endogenous levels of ASIP protein.

Molecular Weight: 15KDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P42127

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only