ASM Polyclonal Antibody - BT-AP14343

ASM Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14343-20, BT-AP14343-50, BT-AP14343-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.

Research Areas: Signal transduction; Neuroscience; Cell biology

Target Protein: SMPD1

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Sphingomyelin phosphodiesterase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P17405; Mouse: Q04519

Synonyms: Sphingomyelin phosphodiesterase;EC 3.1.4.12;Acid sphingomyelinase;aSMase

GeneID: Human: 6609

Research Use Only