Product Description

ASMTL Polyclonal Antibody

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Catalogue Numbers: BS67325-50, BS67325-100

Sizes: 50µl, 100µl

Swiss-Prot: O95671

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. Can also hydrolyze CTP and the modified nucleotides pseudo-UTP, 5-methyl-UTP (m5UTP) and 5-methyl-CTP (m5CTP). Has weak activity with dCTP, 8-oxo-GTP and N4-methyl-dCTP.May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.In addition, the presence of the putative catalytic domain of S-adenosyl-L-methionine binding in the C-terminal region argues for a methyltransferase activity (Probable).

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of ASMTL protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of ASMTL expression in SW620 (A), NIH3T3 (B), mouse pancreas (C), mouse testis (D) whole cell lysates., Immunohistochemical analysis of ASMTL staining in human gastric cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

Bioworld Molecular Weight: ~ 75 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: N-acetylserotonin O-methyltransferase-like protein; ASMTL

Immunogen: Recombinant full length protein of human ASMTL

Conjugate: Unconjugated

Modification: Unmodified