Product Description

ASNA1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-53162-60, E-AB-53162-120, E-AB-53162-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ASNA1

Target Synonym: ARSA 1; ARSA; ArsA arsenite transporter ATP binding homolog 1; ArsA arsenite transporter; ATP binding; E. coli; homolog of; 1; ArsA arsenite transporter; ATP-binding; homolog 1 (bacterial); ARSA I; ARSA-I; ARSA1; ARSAI; Arsenical pump driving ATPase; Arsenical pump-driving ATPase; Arsenical resistance ATPase; Arsenite translocating ATPase; Arsenite transporting ATPase; Arsenite-stimulated ATPase; ASNA 1; ASNA I; ASNA-I; ASNA; ASNA1; Asna1 protein; ASNAI; ATPase ASNA1; GET3; Golgi to ER traffic 3 homolog; hARSA-I; hASNA-I; MGC3821; Transmembrane domain recognition complex 40 kDa ATPase subunit; Transmembrane domain recognition complex; 40kDa; TRC40

Research Areas: Cancer, Cell Biology, Metabolism, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O43681

Background: ASNA1 (also known as TRC40) is a highly conserved ATPase involved in efflux of arsenite and antimonite. Reduced ASNA1 expression is associated with significant inhibition of cell growth, increased apoptosis and increased sensitivity to cisplatin and arsenite.Thus ASNA1 is proposed to be a target to overcome resistance to cancer chemotherapy. In addition, ASNA1 has been identified as an ER targeting factor for tail-anchored proteins in the posttranslational membrane insertion pathway.

Concentration: 1.26 mg/mL

Immunogen: Fusion protein of human ASNA1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only