ASPP1 Polyclonal Antibody - BT-AP14348

ASPP1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14348-20, BT-AP14348-50, BT-AP14348-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.

Research Areas: Cancer; Stem cells

Target Protein: PPP1R13B

Applications: IHC-p, IF, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Apoptosis-stimulating of p53 protein 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q96KQ4; Mouse: Q62415

Synonyms: Apoptosis-stimulating of p53 protein 1;Protein phosphatase 1 regulatory subunit 13B; Apoptosis-stimulating of p53 protein 1; Protein phosphatase 1 regulatory subunit 13B

GeneID: Human: 23368; Mouse: 21981

Research Use Only