ASS1 Polyclonal Antibody - E-AB-18521

ASS1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-18521-60, E-AB-18521-120, E-AB-18521-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ASS1

Target Synonym: Argininosuccinate synthase 1; Argininosuccinate synthase; Argininosuccinate synthetase 1; ASS; Ass-1; ass1; ASSA; ASSY; Citrulline aspartate ligase; Citrulline--aspartate ligase; CTLN1

Research Areas: Cancer, Metabolism, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P00966

Background: ASS1 is a rate-limiting enzyme in the urea cycle. Citrullinemia type I is an autosomal recessive disorder that is caused by a deficiency of the urea cycle enzyme argininosuccinate synthetase (ASS1). Deficiency of ASS1 shows various clinical manifestations encompassing severely affected patients with fatal neonatal hyperammonemia as well as asymptomatic individuals with only a biochemical phenotype.

Concentration: 0.5 mg/mL

Immunogen: Fusion protein of human ASS1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Calculated MW: 47 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only