Ataxin-7L1 Polyclonal Antibody - BT-AP00688

Ataxin-7L1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00688-20, BT-AP00688-50, BT-AP00688-100

Citations, Manuals and MSDS Available upon request.

Background: ATXN7L3 (ataxin-7-like protein 3) is a 347 amino acid transcription protein that belongs to the SGF11 family. ATXN7L3 localizes to nucleus and contains one SCA7 domain and one SGF11-type zinc finger. The SGF11-type zinc finger of ATXN7L3 mediates the interaction with USP22 and ENY2. ATXN7L3 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, which is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, ATXN7L3 contributes to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The ATXN7L3 gene exists as two alternatively spliced isoforms, is conserved in chimpanzee, dog, cow, rat, zebrafish, fruit fly and mosquito, and maps to human chromosome 17q21.1.

Research Areas: Others

Target Protein: ATXN7L1

Applications: IHC-p, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Ataxin-7L1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 88598

UniProt Accession: Human: Q9ULK2; Mouse: Q9CZ05

Synonyms: ATXN7L1; ATXN7L4; KIAA1218; Ataxin-7-like protein 1; Ataxin-7-like protein 4

GeneID: Human: 222255; Mouse: 380753

Research Use Only