Product Description

ATF5 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10583-50, MB10583-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q9Y2D1

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background: ATF5 or Activating transcription factor 5, binds to cAMP inducible promoters and is involved in gene transcription. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF5 plays a role in inhibition of nerve growth factor induced neuronal outgrowth and regulation of neurogenesis.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 31 kDa; Observed MW: 31 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of ATF5 in 3T3 lysates using ATF5 antibody., Western blot analysis of ATF5 in K562, rat Brain, C6, Hela lysates using ATF5 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast cancer using ATF5 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: ATF5; ATFX; Cyclic AMP-dependent transcription factor ATF-5; cAMP-dependent transcription factor ATF-5; Activating transcription factor 5; Transcription factor ATFx

Immunogen: A synthetic peptide of human ATF5

Conjugate: Unconjugated

Modification: Unmodified