Product Description

ATF6B (S425) Polyclonal Antibody

Catalogue Numbers: BS2131-50, BS2131-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q99941

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: ATF-6 is a member of the basic-leucine zipper family of transcription factors. Endoplasmic reticulum stress causes cleavage of transmembrane ATF-6 and transclocation of active ATF-6 to the nucleus. Soluble ATF-6 can exist as either an ATF-6β homodimer or an ATF-6α/β heterodimer. Binding of the ATF-6β homodimer or ATF-6α/β heterodimer to the nuclear transcription factor Y C (NF-YC) induces ER chaperone transcription.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ATF6B (S425) polyclonal antibody detects endogenous levels of ATF6B protein.

Extra Notes: Western blot (WB) analysis of ATF6B pAb at 1:500 dilution
Lane1:The Embryo tissue lysate of Mouse(40ug)
Lane2:C6 whole cell lysate(40ug)
Lane3:CT-26 whole cell lysate(40ug)
Lane4:HEK293T whole cell lysate (40ug)
Lane5:DLD whole cell lysate(40ug)
Lane6:A2780 whole cell lysate(40ug)

Bioworld Molecular Weight: ~ 90 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Cyclic AMP-dependent transcription factor ATF-6 beta; cAMP-dependent transcription factor ATF-6 beta; Activating transcription factor 6 beta; ATF6-beta; Protein G13; cAMP response element-binding protein-related protein; Creb-rp; cAMP-responsive element-binding protein-like 1; Processed cyclic AMP-dependent transcription factor ATF-6 beta; ATF6B; CREBL1; G13; ATF-6β; ATF6β

Immunogen: Synthetic peptide, corresponding to amino acids 390-442 of Human ATF6B.

Conjugate: Unconjugated

Modification: Unmodified