ATG13 Rabbit pAb - ES20862

ATG13 Rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20862-50, ES20862-100

Citations, Manuals and MSDS Available upon request.

Background: Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions.

Alternate Name: Autophagy-related protein 13

Source: Rabbit

Applications: IHC; WB

Dilution: IHC-p 1:50-200, WB 1:1000-2000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human ATG13 AA range: 182-232

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 72kD

Human Gene ID: 9776

Human SWISS Prot NO: O75143

Subcellular Location: Cytoplasm, cytosol. Preautophagosomal structure. Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation.

Research Use Only