Product Description

ATG4A Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB10586-50, MB10586-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The cysteine protease Atg4 is pivotal to autophagosome membrane generation and regμlation. Atg4 primes the Atg8 homologue for lipidation by cleaving its carboxy terminus and exposing its glycine residue for E1-like enzyme Atg7. The Atg8 homologue is transferred to the E2-like enzyme Atg3 before forming the Atg8-PE conjugate. During later stages of autophagy, Atg4 can reverse this lipidation event by cleaving PE, thereby recycling the Atg8 homologue.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC-P, IP

Alternate Names: ATG4A, APG4A, AUTL2, Cysteine protease ATG4A, AUT-like 2 cysteine endopeptidase, Autophagin-2, Autophagy-related cysteine endopeptidase 2, Autophagy-related protein 4 homolog A, hAPG4A

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: A synthetic peptide of human ATG4A

Dilution: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 45 kDa, Observed MW: 45 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8WYN0

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Research Use Only