ATG4B Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A2837-20, A2837-100
Citations, Manuals and MSDS Available upon request.
Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 44kDa
Observed Molecular Weight: 48kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 23192
SWISS: Q9Y4P1
Alternate Names: APG4B; AUTL1; HsAPG4B; ATG4B
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Invasion and Metastasis, Signal Transduction, Cell Biology Developmental Biology, Autophagy, Extracellular Matrix, Ubiquitin, Endocrine Metabolism, Mitochondrial metabolism, Cardiovascular, Heart.
NCBI Alias: ATG4B
Research Use Only