ATG4C Monoclonal Antibody Sizes: 50μl, 100μl Catalogue Numbers: MB67172-50, MB67172-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: Atg4C (ATG4 autophagy related 4 homolog C), also known as AUTL1 (AUTlike 1, cysteine endopeptidase), AUTL3 (AUT-like 3 cysteine endopeptidase), APG4-C, autophagin-3 or cysteine protease ATG4C, is a 458 amino acid tumor suppressor protein belonging to the peptidase C54 family. Encoded by a gene that maps to human chromosome 1p31.3, Atg4C is conserved in chimpanzee, canine, bovine, mouse, rat, chicken and zebrafish. Atg4C is highly expressedin skeletal muscle, heart, liver and testis, and localizes to cytoplasm. Functioning as a cysteine protease, which is necessary for autophagy, Atg4C cleaves the C-terminal region of either MAP1LC3, GABARAPL2 or GABARAP.Atg4C is also inhibited by N-ethylmaleimide. Category: Primary Antibody Reactivity: Mouse Host: Mouse Applications: WB Alternate Names: APG4C, AUTL1, AUTL3, Cysteine protease ATG4C, AUT-like 3 cysteine endopeptidase, Autophagin-3, Autophagy-related cysteine endopeptidase 3, Autophagy-related protein 4 homolog C Clonality: Monoclonal Conjugate: Unconjugated Modification: Unmodification Immunogen: Recombinant fusion protein of human ATG4C. The exact sequence is proprietary. Dilution: WB (1/500 - 1/1000) Purification: This antibody is purified through a protein G column. Specificity: Recognizes endogenous levels of ATG4C protein. Molecular Weight: ~ 52 kDa Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. SwissProt: Q811C2 Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide. Research Use Only