Product Description

ATG4C Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS6137-50, BS6137-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q96DT6

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB 1:500 - 1:2000

Background: Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ATG4C polyclonal antibody detects endogenous levels of ATG4C protein.

Bioworld Molecular Weight: ~ 53 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot (WB) analysis of ATG4C pAb at 1:2000 dilution
Lane1:U-87MG whole cell lysate(20ug)
Lane2:PC3 whole cell lysate(20ug)
Lane3:K562 whole cell lysate(40ug)
Lane4:The Brain tissue lysate of Rat(10ug)
Lane5:AML-12 whole cell lysate(40ug)
Lane6:The Muscle tissue lysate of Mouse(40ug)

Alternative Name: APG4 autophagy 4 homolog C (S. cerevisiae); APG4 autophagy 4 homolog C; APG4 C; APG4C; ATG 4C; ATG4 autophagy related 4 homolog C (S. cerevisiae); Atg4c; ATG4C; AUT (S. cerevisiae) like 1; cysteine endopeptidase; AUT like 1; cysteine endopeptidase (S. cerevisiae); AUT like 1; cysteine endopeptidase; AUT like 3 cysteine endopeptidase; AUT-like 3 cysteine endopeptidase; AUTL1; AUTL3; Autophagin 3; Autophagin-3; Autophagy related cysteine endopeptidase 3; Autophagy related protein 4 homolog C

Immunogen: Recombinant full length Human ATG4C.

Conjugate: Unconjugated

Modification: Unmodified