ATG4C Polyclonal Antibody
Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sizes: 50µl, 100µl
Catalogue Numbers: BZ16818-50, BZ16818-100
Swiss-Prot: Q96DT6
Host: Rabbit
Reactivity: Human
Applications: WB, IHC-P, FC
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100
Background: Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Calculated MW: 52 kDa; Observed MW: 52 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Atg4C in Jurkat lysates using ATG4C antibody.
Alternative Name: ATG4C; APG4C; AUTL1; AUTL3; Cysteine protease ATG4C; AUT-like 3 cysteine endopeptidase; Autophagin-3; Autophagy-related cysteine endopeptidase 3; Autophagy-related protein 4 homolog C
Immunogen: A synthesized peptide derived from human Atg4C
Conjugate: Unconjugated
Modification: Unmodified