ATG5 (3C7) Mouse mAb - EM1374

ATG5 (3C7) Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1374-50, EM1374-100

Citations, Manuals and MSDS Available upon request.

Background: Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.

Alternate Name: APG5, APG5L, ASP, Autophagy protein 5 antibody

Source: Mouse

Applications: WB, IHC

Dilution: WB  1:5, 000-10, 000 IHC 1:100-200

Reactivity: Human, Mouse, Rat

Immunogen: Recombinant Protein

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 55kDa

Human Gene ID: 9494

Human SWISS Prot NO: Q9H1Y0

Subcellular Location: Cytoplasm,  Membrane

Research Use Only