ATG5 mouse Monoclonal Antibody (3C7) - BT-MCA0008

ATG5 mouse Monoclonal Antibody (3C7)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0008-20, BT-MCA0008-50, BT-MCA0008-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.

Research Areas: Cell biology; Cancer; Metabolism

Target Protein: ATG5

Applications: IF, ICC, WB, IHC-p, IP

Reactivity: Human,Mouse,Rat

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Autophagy protein 5

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9H1Y0; Mouse: Q99J83; Rat: Q3MQ06

Synonyms: Autophagy protein 5; APG5-like; Apoptosis-specific protein; ATG5; APG5L; ASP

GeneID: Human: 9494

Research Use Only