ATG7 mouse Monoclonal Antibody (3D6) - BT-MCA0191

ATG7 mouse Monoclonal Antibody (3D6)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0191-20, BT-MCA0191-50, BT-MCA0191-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.

Research Areas: Cancer; Signal transduction; Metabolism; Cardiovascular; Cell biology

Target Protein: ATG7

Applications: IF, ICC, IHC-p

Reactivity: Human,Mouse,Rat

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Ubiquitin-like modifier-activating enzyme ATG7

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O95352; Mouse: Q9D906; Rat: Q641Y5

Synonyms: Ubiquitin-like modifier-activating enzyme ATG7; ATG12-activating enzyme E1 ATG7; Autophagy-related protein 7; APG7-like; hAGP7; Ubiquitin-activating enzyme E1-like protein; ATG7; APG7L

GeneID: Human: 10533

Research Use Only