ATIC Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5559-20, A5559-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 65kDa
Observed Molecular Weight: 62kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 471
SWISS: P31939
Alternate Names: PURH; AICAR; AICARFT; IMPCHASE; HEL-S-70p; ATIC
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Signal Transduction, Endocrine Metabolism, Nucleotide metabolism.
NCBI Alias: ATIC
Research Use Only