Product Description

ATM (9F7) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3299-50, MB3299-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q13315

Host: Mouse

Reactivity: Human, Rat, Mouse

Applications: IHC-P

All Applications: IHC: 1/50-1/100

Background: The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: -

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using ATM antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval., Immunohistochemical analysis of paraffin-embedded Human tonsils using ATM antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Alternative Name: ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated

Immunogen: Synthetic peptide conjugated to KLH.

Conjugate: Unconjugated

Modification: Unmodified