Product Description

ATP-Citrate Lyase (C-term) Mouse Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA10817-50, RA10817-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: ATP citrate lyase (ACLY) Homo sapiens ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440, 000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014],

Reactivity: Human, Mouse, Monkey

Host: Mouse

Applications: WB, ICC, FC

Alternate Names: ACL, Acly, ACLY_HUMAN, ATP citrate (pro-S) lyase, ATP citrate lyase, ATP citrate synthase, ATP-citrate (pro-S-)-lyase, ATP-citrate synthase, ATPcitrate synthase, ATPCL, Citrate cleavage enzyme, CLATP, EC 2.3.3.8, OTTHUMP00000164773.

Clonality: Monoclonal

Dilution: wb 1:1000 icc 1:150 fcm 1:100

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Human Gene ID: 47

Protein Molecular Weight（KDa): 120

Molecular Weight: 120

Research Use Only