ATP Citrate lyase Monoclonal Antibody-MB10590

ATP Citrate lyase Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10590-50, MB10590-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P53396

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 121 kDa; Observed MW: 121 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of ATP Citrate lyase in A549 using ATP Citrate lyase antibody, and DAPI., Western blot analysis of ATP citrate lyase in K562, C6, 3T3, Hela lysates using ATP citrate lyase antibody.

Alternative Name: ACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme

Immunogen: A synthetic peptide of human ATP citrate lyase

Conjugate: Unconjugated

Modification: Unmodified