Product Description

ATP2A1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90108-50, BS90108-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O14983(Human) Q8R429(Mouse) Q64578(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC FC

All Applications: WB:1:500-1:1,000
IHC:1:50-1:200
FC:1:50-1:100

Background: Key regulator of striated muscle performance by acting as the major Ca2+ ATPase responsible for the reuptake of cytosolic Ca2+ into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.

Purification and Purity: Peptide affinity purified.

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: ATP2A1 polyclonal antibody detects endogenous levels of ATP2A1 protein.

Bioworld Molecular Weight: 110 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of ATP2A1 on different lysates using anti-ATP2A1 antibody at 1/500 dilution.
Positive control:
Lane 1: Mouse skeletal muscle tissue
Lane 2: Human skeletal muscle tissue, Immunohistochemical analysis of paraffin-embedded rat skeletal muscle tissue using anti-ATP2A1 antibody. Counter stained with hematoxylin.

Alternative Name: SERCA1, SR Ca(2+)-ATPase 1, ATP2A1, fast twitch skeletal muscle isoform, AT2A1, ATP2A, ATP2A1, ATPase Ca++ transporting cardiac muscle fast twitch 1, ATPase Ca++ transporting fast twitch 1, ATPase, Ca(2+)-transporting fast twitch 1, Calcium pump 1, Calcium transporting ATPase sarcoplasmic reticulum type fast twitch skeletal muscle isoform, Calcium-transporting ATPase sarcoplasmic reticulum type, EC 3.6.3.8, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, Fast skeletal muscle SR calcium ATPase, OTTHUMP00000162561, OTTHUMP00000162562, Sarcoendoplasmic reticulum calcium ATPase, Sarcoplasmic reticulum Ca(2+)-ATPase 1, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, SERCA 1, SERCA1, SERCA1 truncated isoform, included, SR Ca(2+) ATPase 1, SR Ca(2+)-ATPase 1,

Immunogen: Synthetis peptide within rat ATP2A1 aa 20-50.

Conjugate: Unconjugated

Modification: Unmodified