ATP5J2 Polyclonal Antibody
Catalogue Numbers: BS60484-50, BS60484-100
Sizes: 50µl, 100µl
Alternative Name: ATP synthase subunit f, mitochondrial; ATP5J2
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: A6ND55
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. ATP5J2, also know as ATP synthase subunit f, mitochondrial, is a 94 amino acid mitochondrion inner membrane that belongs to the ATPase F chain family. Mitochondrial dysfunction is prominent in Alzheimer's disease (AD). A failure of one or more of the mitochondrial electron transport chain enzymes, or of F(1)F(0)-ATPase (ATP synthase), could compromise brain energy stores, generate damaging reactive oxygen species (ROS), and lead to neuronal death. Existing as two alternatively spliced isoforms, the ATP5J2 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 7q22.1.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ATP5J2 polyclonal antibody detects endogenous levels of ATP5J2 protein.
Bioworld Molecular Weight: ~ 11 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of ATP5J2 polyclonal antibody at 1:500 dilution
Lane 1: HEK293T whole cell lysate
Lane 2: Raw264.7 whole cell lysate
Lane 3: H9C2 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human ATP5J2.
Conjugate: Unconjugated
Modification: Unmodified