Product Description

ATP5J2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60484-50, BS60484-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked mμlti-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. ATP5J2, also know as ATP synthase subunit f, mitochondrial, is a 94 amino acid mitochondrion inner membrane that belongs to the ATPase F chain family. Mitochondrial dysfunction is prominent in Alzheimer's disease (AD). A failure of one or more of the mitochondrial electron transport chain enzymes, or of F(1)F(0)-ATPase (ATP synthase), coμld compromise brain energy stores, generate damaging reactive oxygen species (ROS), and lead to neuronal death. Existing as two alternatively spliced isoforms, the ATP5J2 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 7q22.1.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: ATP synthase subunit f, mitochondrial, ATP5J2

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human ATP5J2.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: ATP5J2 polyclonal antibody detects endogenous levels of ATP5J2 protein.

Molecular Weight: ~ 11 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: A6ND55

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only