Product Description

ATP6 Polyclonal Antibody

Catalogue Numbers: BS1681-50, BS1681-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P00848

Host: Rabbit

Reactivity: Mouse,Rat

Applications: WB

All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200

Background: ATP6, also known as MT-ATP6, ATPASE6 or MTATP6, is a 226 amino acidmulti-passmembrane protein that localizestomitochondria and functions as a component of the F0 proton channel, playing a direct role in the transport of protons acrossthe mitochondrial membrane. Defectsin the gene encoding ATP6 are the cause of infantile bilateralstriatal necrosis, Leigh syndrome (LS),Leber hereditary optic neuropathy(LHON) and neurogenic muscle weakness, ataxia, and retinitis pigmentosa (NARP), all of which are neurological or retinal disorders. The gene encoding ATP6 exists as part of themitochondrial genome.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ATP6 polyclonal antibody detects endogenous levels of ATP6 protein.

Extra Notes: Western blot (WB) analysis of ATP6 polyclonal antibody at 1:1000 dilution
Lane1:The muscle tissue lysate of Rat (47μg)
Lane2:The muscle tissue lysate of Mouse(37μg)

Bioworld Molecular Weight: ~ 25 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: ATP synthase subunit a; F-ATPase protein 6; Mtatp6; Atp6; Atpase6; mt-Atp6

Immunogen: A synthetic peptide corresponding to amino acids 55-70 of Mouse ATP6.

Conjugate: Unconjugated

Modification: Unmodified