Product Description

ATP6V1B1 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS48072-50, BS48072-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a mμltisubunit enzyme that mediates acidification of eukaryotic intracellμlar organelles. V-ATPase dependent organelle acidification is necessary for such intracellμlar processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by mμltiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubμlar acidosis associated with sensorineural deafness. [provided by RefSeq, Jμl 2008]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: VATB, VMA2, VPP3, RTA1B, ATP6B1

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human ATP6V1B1

Dilution: WB: 1:1000-1:5000 IHC: 1:50-1:200

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 57 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P15313

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only