Product Description

ATPBD3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA22241-50, RA22241-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Plays a central role in 2-thiolation of mcm (5)S (2)U at tRNA wobble positions of tRNA (Lys), tRNA (Glu) and tRNA (Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position., pathway:tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis., similarity:Belongs to the ttcA family. CTU1/NCS6/ATPBD3 subfamily., subunit:Component of a complex at least composed of URM1, CTU2/NCS2 and ATPBD3/NCS6. May for a heterodimer with CTU2/NCS2.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: CTU1, ATPBD3, NCS6, Cytoplasmic tRNA 2-thiolation protein 1, ATP-binding domain-containing protein 3, Cancer-associated gene protein, Cytoplasmic tRNA adenylyltransferase 1

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight: 36

Protein Molecular Weight (kDa): 36

Storage: -20°C/1 year

Human Gene ID: 90353

Human SwissProt Number: Q7Z7A3

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only