ATPBD3 rabbit pAb - ES7936

ATPBD3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7936-50, ES7936-100

Citations, Manuals and MSDS Available upon request.

Background: function:Plays a central role in 2-thiolation of mcm (5)S (2)U at tRNA wobble positions of tRNA (Lys), tRNA (Glu) and tRNA (Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position., pathway:tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis., similarity:Belongs to the ttcA family. CTU1/NCS6/ATPBD3 subfamily., subunit:Component of a complex at least composed of URM1, CTU2/NCS2 and ATPBD3/NCS6. May for a heterodimer with CTU2/NCS2.,

Alternate Name: CTU1; ATPBD3; NCS6; Cytoplasmic tRNA 2-thiolation protein 1; ATP-binding domain-containing protein 3; Cancer-associated gene protein; Cytoplasmic tRNA adenylyltransferase 1

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human ATPBD3. AA range:291-340

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 36kD

Human Gene ID: 90353

Human SWISS Prot NO: Q7Z7A3

Subcellular Location: Cytoplasm

Research Use Only