ATRIP (phospho Ser224) rabbit pAb - ES7733

ATRIP (phospho Ser224) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7733-50, ES7733-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012],

Alternate Name: ATRIP; AGS1; ATR-interacting protein; ATM and Rad3-related-interacting protein

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human ATRIP around the phosphorylation site of Ser224. AA range:190-239

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 86kD

Human Gene ID: 84126

Human SWISS Prot NO: Q8WXE1

Subcellular Location: Nucleus. Redistributes to discrete nuclear foci upon DNA damage.

Research Use Only