Product Description

AurA (Phospho-Ser342) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65168-50, BS65168-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: aurora kinase A(AURKA) Homo sapiens The protein encoded by this gene is a cell cycle-regμlated kinase that appears to be involved in microtubμle formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Mμltiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jμl 2008],

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC-p, IF(paraffin, section), ELISA

Alternate Names: AURKA, AIK, AIRK1, ARK1, AURA, AYK1, BTAK, IAK1, STK15, STK6, Aurora kinase A, Aurora 2, Aurora/IPL1-related kinase 1, ARK-1, Aurora-related kinase 1, hARK1, Breast tumor-amplified kinase, Serine/threonine-protein kinase 15, Serine/threonin

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: The antiserum was produced against synthesized peptide derived from human AurA around the phosphorylation site of Ser342. AA range:311-360

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity: Phospho-ARK-1 (S342) Polyclonal Antibody detects endogenous levels of ARK-1 protein only when phosphorylated at S342.

Molecular Weight: /

Pathway: Epigenetic Writers and Erasers of Histone H3,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O14965

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only