Autotaxin Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA22261-50, RA22261-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2) Homo sapiens The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008], Reactivity: Human, Mouse, Rat Host: Rabbit Applications: WB, ELISA Alternate Names: ENPP2, ATX, PDNP2, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, E-NPP 2, Autotaxin, Extracellular lysophospholipase D, LysoPLD Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. Molecular Weight: 98 Protein Molecular Weight (kDa): 98 Storage: -20°C/1 year Human Gene ID: 5168 Human SwissProt Number: Q13822 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only