Product Description

AVP Receptor V3 (D314) Polyclonal Antibody

Catalogue Numbers: BS2968-50, BS2968-100

Sizes: 50µl, 100µl

Alternative Name: Vasopressin V1b receptor; V1bR; AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor; AVPR1B; AVPR3; VPR3

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P47901

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IF

All Applications: WB: 1:500~1:1000
IF: 1:50~1:200

Background: Vasopressin (AVP), the antidiuretic hormone, is a cyclic nonpeptide that is involved in the regulation of body fluid osmolality. AVP mediates its effects through a family of G protein coupled receptors, the vasopressin receptors type V1a, V2 and V3 (also designated V1b). The AVP receptor V3 is preferentially expressed in the pituitary and stimulates the release of adrenocorticotropic hormone (ACTH) in response to AVP by mobilizing intracellular calcium stores. AVP receptor antagonists may have potential therapeutic effects in hypertension, congestive heart failure, nephrotic syndrome and ACTH-secreting tumors.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: AVP Receptor V3 (D314) polyclonal antibody detects endogenous levels of AVP Receptor V3 protein.

Bioworld Molecular Weight: ~ 47 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of AVP Receptor V3 (D314) polyclonal antibody at 1:500 dilution
Lane 1: HepG2 cell lysate
Lane 2: Mouse liver tissue lysate
Lane 3: Rat lung tissue lysate

Immunogen: Synthetic peptide, corresponding to amino acids 300-350 of Human AVP Receptor V3.

Conjugate: Unconjugated

Modification: Unmodified