Product Description

Axin 2 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10599-50, MB10599-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q9Y2T1

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3β, Dvl, and β-catenin and promotes the GSK-3β-mediated phosphorylation and subsequent degradation of β-catenin .Down-regulates beta-catenin.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Axin 2 in K562, C6, 3T3, HelaLysates using Axin 2 antibody.

Bioworld Molecular Weight: Calculated MW: 94 kDa; Observed MW: 94 kDa

Specificity: IgG

Alternative Name: Axil; Axin like protein; Axin2; Axis inhibition protein 2; Conductin

Immunogen: A synthetic peptide of human Axin 2

Conjugate: Unconjugated

Modification: Unmodified