Axin 2 Polyclonal Antibody
Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sizes: 50µl, 100µl
Catalogue Numbers: BZ16795-50, BZ16795-100
Swiss-Prot: Q9Y2T1
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-P, ICC/IF
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Background: Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3β, Dvl, and β-catenin and promotes the GSK-3β-mediated phosphorylation and subsequent degradation of β-catenin.Down-regulates beta-catenin.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Calculated MW: 94 kDa; Observed MW: 94 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Axin2 in SW480 lysates; PC-12 lysates using Axin 2 antibody.
Alternative Name: Axil; Axin like protein; Axin2; Axis inhibition protein 2; Conductin
Immunogen: A synthesized peptide derived from human Axin2
Conjugate: Unconjugated
Modification: Unmodified